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The NFL world was stunned when the Indianapolis Colts, desperate for quarterback options, lured 44-year-old Philip Rivers out of retirement. The veteran, now a grandfather, is reportedly going to start over rookie Riley Leonard against the Seattle Seahawks on Sunday. He will have his work cut out for him in Week 15 against a bruising Seattle defense.

Kickoff from Lumen Field is set for 4:25 p.m. ET on CBS and Paramount+. The Seahawks are 13.5-point favorites, per the latest Colts vs. Seahawks odds at DraftKings, and the over/under for total points scored is 42.5. Before making any Colts vs. Seahawks picks of your own, make sure to look at the top NFL picks from the SportsLine Projection Model, which simulates every NFL game 10,000 times. 

Where to watch Colts vs. Seahawks on Sunday

When: Sunday, Dec. 14
Time: 4:25 p.m. ET
TV: CBS
Stream: Paramount+  
Follow along: CBS Sports App

Colts vs. Seahawks betting preview

Odds: Seahawks -13.5, over/under 42.5

Indianapolis is both 7-6 ATS and to the Over. Seattle is 10-3 ATS and 8-5 to the Over. The Under has hit in three of the last five Colts games, while the Over has hit in three of the last five Seahawks games. Seattle has covered in four of its last five.

Colts vs. Seahawks SGP

Bet it at DraftKings:

Model's Colts vs. Seahawks score prediction, picks

Seattle is a massive home favorite, given that the Colts will be starting a 44-year-old coming off the couch. Indianapolis wins in just 21% of the model's simulations, which offers notable value for the +700 Colts money line. Indy covers the big spread in 56% of the sims and the Over hits 59% of the time.

Colts vs. Seahawks score prediction: Seahawks 29, Colts 17

Bet the Over at DraftKings:

Want more Week 15 NFL picks?

You've seen the model's best bets for Indianapolis Colts vs. Seattle Seahawks. Now, get against the spread, total and money-line picks for every Week 15 NFL game here, all from the model that's simulated every game 10,000 times.